Soluble OX40L is associated with presence of autoantibodies in early rheumatoid arthritis
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منابع مشابه
Soluble OX40L is associated with presence of autoantibodies in early rheumatoid arthritis
INTRODUCTION OX40 and its ligand OX40L are key components in the generation of adaptive memory response and provide necessary co-stimulatory signals for activated effector T cells. Here we investigate the dual roles of the membrane and soluble (s) forms of OX40 and OX40L in plasma and synovial fluid and their association with autoantibodies and disease activity in rheumatoid arthritis (RA). M...
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(e--mail: [email protected]) Although the incidence and prevalence of individual autoimmune diseases are not high (table), the population burden of the disease is large and underestimated. Serum autoantibodies, which appear long before onset of clinical disease, are a characteristic feature, as recently emphasised by Markus Nielen and colleagues. Studying patients with rheumatoid arth...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2014
ISSN: 1478-6354
DOI: 10.1186/s13075-014-0474-4